De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
نویسندگان
چکیده
منابع مشابه
De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
Of the currently identified protein sequences, 99.6% have never been observed in the laboratory as proteins and their molecular function has not been established experimentally. Predicting the function of such proteins relies mostly on annotated homologs. However, this has resulted in some erroneous annotations, and many proteins have no annotated homologs. Here we propose a de-novo function pr...
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2016
ISSN: 2041-1723
DOI: 10.1038/ncomms13424